Pharmaceutical name:

英文药名：

Radix Trichosanthis

Latin botanical name:

拉丁學名：

Trichosanthes kirilowii, Maxim, or Trichosanthes japonica, Regel.

Pron. in Japanese:

日語發音：

tenkafun

Pron. in Korean:

韓語發音：

chonhwabun

Pron. in Cantonese:

粤語發音：

tin1  faa1 fan2

Other Names:

別名：

tian hua fen originally called gua lou gen, also call ed hua fen.

原名括簍根，簡稱花粉

Common Name:

英文名：

trichosanthes root

Distribution:

分佈：

throughout China, especially in Shandong, Hebei, Shanxi, Shaanxi

全中國，尤其是山東，河北，山西，陕西。

Properties (characteristics)

sweet, slightly bitter, slightly cold

味甘微苦酸微寒

Channels (meridians) entered:

lung, stomach

歸肺、胃 經

Actions & Indications:

Clears lung heat, dissolves phlegm, for cough with thick phlegm, rid of toxicity, expels pus; for treatment of chlorion epithelioma, hydatidiform mole.

用於熱病煩渴， 肺熱 燥咳， 內熱消渴 ， 瘡瘍腫毒﹐治絨毛膜上皮癌及惡性葡萄胎。

Modern Applications:

hydatidiform tumor:

tian zao combination formula: tian hua fen 60mg, ya zao jiao 25 mg ground into fine powder and put into capsules. Insert into vagina once every 5 to 7 day. Treated 7 patients. Those had hydatiform tumors, 5 patients, all healed. 2 patients with chorion-epothelioma (絨 癌 ) not effective. Using tian zao combination formula and chemo therapy: 10 patients, healed 13, ineffective 6. Using tian zao combination formula and chemo therapy plus surgery: 65 patients, healed 54, ineffective 11. [4]

Medical Function:

• 1. Causes miscarriage

• 2. Effects on immune system

• 3. Anti HIV

• 4. Anti tumor (immunotoxin,IT)

• 5. Inhibits synthesis of protein

• 6. Others:   (1) affects blood sugar    (2) anti bacteria

• 7. Penetrating parts of the body

• 8. Toxicity

Chemical ingredients:

化學成份：

1. Protein

1. Trichosanthin with molecule weight of 24,000, and the isoelectric point (等 電 點 ) is 9.4, is a simple protein that does not possess phosphorous acid groups. Trichosanthin is being used clinically in inducing delivery and it possesses effects of anti hydatiform tumor (葡 萄 胎 ) and HIV.

2. Karasurin with molecule weight of 28,000, possesses the effects of abortion in and inducing delivery,  pregnant laboratory mice. It also inhibits the imumme system

3. Apha-momorcharin, molecule weight 29,000 and beta-momorcharin, molecule  weight 28,000, both contain 1.6% and 1.3% of nertral sugar. Like trichosanthin,  they also contain asparagic acid and glutamic acid, and do not contain cysteine (半 胱 氨 酸 ).

2. Polysaccharides

1. It is a source of calories. It improves the imumme system, and possesses effects of anti cancer and the toxic activities from the cells. The multi-sugar consists of glucose, fruitose, cerebrose (半 乳 糖 )， mannose (甘 露 糖 ), xylose (木 糖 ) and small amount of protein.

3. Plant Agglutinin （ 凝 集 素 )

1. TK I, TK II, TK II

4. Enzyme

5. Amino Acids

6. Others

More to be loaded

Dosage:

用量：

9 - 15 g

Samples of formulae:

處方舉例：

to be loaded

Modern Research:

现代研究：

to be loaded

Cautions:

禁忌：

not to be used by pregnant women or in cases of pixu (speen deficient) or weixu (stomach deficient)。

Large dosages and/or long term usage can be toxic to kidneys.

懷孕或脾虛者忌用。大劑量或長期服用可能對 腎臟有毒。