Pharmaceutical name:

英文藥名﹕

Botanical name:

學名﹕

Gelsemium elegans  Benth.

Pron. in Japanese:

日語發音﹕

Pron. in Korean:

韓語發音﹕

Pron. in Cantonese:

粵音﹕

Other Names:

別名﹕

duan chang cao 斷腸草, ye ge 野葛, da cha teng 大茶藤

Common Name:

英文名﹕

poison hemlock

Distribution:

產地﹕

Properties

(characteristics)﹕

性味﹕

辛﹐溫﹐大毒。

acrid, warm, very toxic

歸經﹕

Medical functions:

藥理﹕

Actions & Indications:

主治﹕

Mainly for external use.

Chemical ingredients:

化學成份﹕

Dosage:

用量﹕

0.1 g to 0.15 g

每日量﹕0.1 克~ 0.15 克。

Samples of formulae

:處方舉例﹕

Modern Research:

現代研究﹕

• Rujjanawate C, Kanjanapothi D, Panthong A.

Laboratory of Natural Products, Faculty of Medicine,

Chulabhorn Research Institute, Research Center at Chiangmai University,

Chiangmai University, Chiangmai 50200, Thailand. crujjana@med.cmu.ac.th

Gelsemium elegans Benth. (Loganiaceae), a toxic plant indigenous to southeastern

Asia, is well known among hilltribes as an effective means for committing suicide.

A crude alkaloidal fraction from its leaves was isolated by conventional acid-base

extraction. Tests in animals showed that the alkaloids exerted analgesic and

anti-inflammatory effects. At a lethal dose, the alkaloids produced violent clonic

convulsions that led to respiratory failure. Since the convulsions could be prevented

by pentobarbital or diazepam and potentiated by reserpine, it is postulated that the

alkaloids act centrally against GABA action.

PMID: 14522437 [PubMed - indexed for MEDLI

Toxicity & Cautions:

毒素與禁忌﹕

Whole plant is toxic. It is for external use only. The young leaves are especially toxic.

There is no effective antidote. The commonly used therapy is gastric lavage,

promoting vomiting and diarrhea. See "Modern Research" itme above.

全株有毒。只作外用。新生幼葉尤毒。沒有特效 藥。一般處理方法﹕洗胃﹐

催嘔﹐催瀉。看上條 “現代研究”。